Polypyrrole-Ag/AgCl Nanocomposite-Enabled Exhaled Breath-Acetone Monitoring Non-Invasive Biosensor for Diabetes Diagnostics

The state-of-the-art diabetes diagnosis is concerned with developing non-invasive nano-enabled exhaled breath-acetone detection strategies. This communication details the potential of polypyrrole(PPy)– Silver/silver chloride (Ag/AgCl) ternary nanocomposites (NCs) for monitoring low-trace acetone in human breath diagnosis. PPy–Ag/AgCl NCs were synthesized through situ chemical oxidative polymerization aniline by silver nitrate presence hydrochloric acid. morphological analysis revealed existence spherical Ag/AgCl nanoparticles (diameter ∼50 nm) embedded PPy matrix nano fibrillar morphology ∼20 nm). structural investigations confirm co-existence PPy, Ag and AgCl nanocomposite. NC exhibited manifold superior sensing performance towards low trace (as as ∼1 ppm) excellent sensitivity (∼20%), prompt response (∼20 s), fast recovery (∼100s), linear detecting range, high repeatability at room temperature compared to pristine PPy. It attributed synergistic effects due physicochemical merits all precursors. Moreover, it showed stability selectivity prominent interfering VOCs varying humidity. opens a new window non-invasive, economic, energy-efficient point-of-care sensors diagnosing humans and, revolutionizing clinical diagnostics personal healthcare.